Acetone → HCID 14407713, compound

Participants

Reaction Conditions

Reaction Steps

Sodium hydroxide in an amount of more than equivalent is added to the above-mentioned 4-[3-(hydroxymethyl)phenylhydrazono]-2-phenyl-2-oxazolin-5-one in an aprotic organic solvent such as acetone, dioxane, tetrahydrofuran, dimethylformamide and methyl ethyl ketone and after reacting the mixture, hydrochloric acid is added to the mixture to adjust the pH to from 1 to 4, and then the thus adjusted mixture is heated to a temperature of lower than 100° C., preferably from 30° to 60° C., thereby obtaining a novel compound, 1-[3-(hydroxymethyl)phenyl]-5-phenyl-1H-1,2,4,-triazole-3-carboxylic acid represented by the formula (V): ##STR87##

Provenance & Evidence