Formaldehyde → HCID 13661368, compound

HRID 620138Notes

Reaction equation

HRID 620138 reaction equation
[CH2:1]([P:12](=[O:21])([O:17][CH2:18][CH2:19][CH3:20])[O:13][CH2:14][CH2:15][CH3:16])[P:2](=[O:11])([O:7][CH2:8][CH2:9][CH3:10])[O:3][CH2:4][CH2:5][CH3:6].C=O.[CH2:24](NCC)C>CO>[C:1]([P:2](=[O:11])([O:7][CH2:8][CH2:9][CH3:10])[O:3][CH2:4][CH2:5][CH3:6])([P:12](=[O:21])([O:13][CH2:14][CH2:15][CH3:16])[O:17][CH2:18][CH2:19][CH3:20])=[CH2:24]

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 8021DiethylamineHCID 600928HCID 600928, compound

Product 1

HCID 13661368HCID 13661368, compoundYield 71.9%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

5.97 g (17.4 mmol) of tetra-n-propyl methylenebisphosphonate, 2.61 g (86.8 mmol) of paraformaldehyde and 1.27 g (17.4 mmol) of diethylamine are combined with the same reactants and the same conditions as described above in Example I. This mixture is then refluxed for 46 hours. After the methanol is eliminated as described above in Example I, 4.46 g of tetra-n-propyl ethenylidenebisphosphonate is produced as a clear oil.

Workup

  1. temperatureThis mixture is then refluxed for 46 hours

Sources & evidence

ORD record
ord-0e34dacef55b446c996858a1eaef947a
Source dataset
uspto-grants-1989_04
Patent number
US04820698

Reaction notes

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