反应详情

2.9 (12.6 mmol) of 6-(2-amino-indan-5-yl)-4,5-dihydropyridazin-3(2H)-one are dissolved in a mixture of 30 ml of dioxan and 10 ml of acetone, and 1.42 g (14 mmol) of triethylamine and 2.8 g of p-fluorobenzenesulphonyl chloride are added. After 2 hours, the mixture is evaporated, water is added to the residue, and the reaction product is filtered off with suction and recrystallised from glacial acetic acid.

1. additionare added
2. customthe mixture is evaporated
3. additionwater is added to the residue
4. filtrationthe reaction product is filtered off with suction
5. customrecrystallised from glacial acetic acid