[4-(2-Ethyl-imidazo[4,5-c]quinolin-1-yl)-butyl]-carbamic acid tert-butyl ester → 4-(2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butan-1-amine

Participants

Reaction Steps

A solution of [4-(2-Ethyl-imidazo[4,5-c]quinolin-1-yl)-butyl]carbamic acid tert-butyl ester of formula 5 obtained in step V in trifluroacetic acid was stirred at 40° C. for 4 hrs. Reaction mixture was then poured on ice-water mixture and extracted with chloroform. Organic layer was dried over sodium sulphate and concentrated under deduced pressure to afford 4-(2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl) butan-1-amine of formula 6.

Provenance & Evidence