Phenylacetyl chloride → HCID 21246502, compound

Participants

Reaction Steps

6.0 g (28.9 millimoles) of 1,4-dihydro-4-imino-1-phenylpyridazine hydrochloride in 50 ml of phenylacetyl chloride were kept at 120° C. for 6 hours, while stirring. The mixture was cooled and then evaporated down, and the residue was treated with methanol/methyl tert.-butyl ether. The solid was filtered off under suction and recrystallized first from ethanol and then from ethanol/acetone with the addition of active charcoal. 3.9 g (41% of theory) of 1,4-dihydro-1-phenyl-4-[(phenylacetyl)-imino]-pyridazine hydrochloride were isolated as pale beige crystals of melting point 208°-210° C.

Provenance & Evidence