Piperidine → HCID 21247225, compound

Participants

Reaction Steps

A mixture of 0.5 g of 1-(2'-hydroxy-3'-chloropropyl)-4-nitro-1,2,3-triazole and 3 g of piperidine in 10 ml of THF is refluxed for 1 hr with stirring. The solvent and excess piperidine are removed. The residue is dissolved in chloroform and washed with 5 ml of 1% NaOH solution. The solvent is evaporated to dryness, dissolved in dilute HCl solution washed with chloroform.

Provenance & Evidence