HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-bromopropionate → HCID 10413093, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-bromopropionate | HCID 79040 | — |
| Reactant | Benzyl (2-oxo-5-phenyl-2,3-dihydro-1h-benzo[e][1,4]diazepin-3-yl)carbamate | HCID 2756242 | — |
| Product | HCID 10413093 | HCID 10413093 | — |
Reaction Steps
The procedure of Example 134 was carried out using equivalent amounts of 1,3-dihydro-3-phenylmethyloxycarbonylamino-5-phenyl-2H-1,4-benzodiazepin-2-one and ethyl bromopropionate. The product was purified by chromatography on silica gel (hexane-ethyl acetate elution). The combined product fractions were evaporated to dryness in vacuo and crystallized to give the title compound which was dried at 65° C.: m.p. 57°-59° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04820834 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-3660f1edf7a84c4ba988ba00214131c0 |
| Source note | uspto-grants-1989_04 |