HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-(3-nitrophenoxy)tetradecanoate → 2-(m-Aminophenoxy)-myristic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-(3-nitrophenoxy)tetradecanoate | HCID 14122414 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(m-Aminophenoxy)-myristic acid ethyl ester | HCID 14122415 | — |
Reaction Steps
A solution of 154 g (0.39 mol) of 2-(m-nitrophenoxy)-myristic acid ethyl ester in 500 ml of ethanol is placed in an autoclave. An amount of 8 ml of Raney nickel is added. Reduction of the nitro group is carried out with hydrogen gas at an initial pressure of 10-10.5 MPa and a temperature of 65° C. After the reduction (2 h) the solvent is removed by evaporation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04822729 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-55fd5ee8d23f4e25b616d18e1d65be2f |
| Source note | uspto-grants-1989_04 |