反应详情

To a suspension of 1-hydroxyimino-1-(3-pyridyl)acetone (1.5 g) in a mixture of dioxane (30 ml) and ethanol (8 ml) were added conc. ammonia water (40 ml) and 2-methoxybenzaldehyde (1.24 g), and the mixture was stirred at ambient temperature for 8 days. After evaporation, the mixture was triturated with chloroform to give 1-hydroxy-2-(2-methoxyphenyl)-4-methyl-5-(3-pyridyl)imidazole (1.65 g).

1. customAfter evaporation
2. customthe mixture was triturated with chloroform