反应详情

Prepared from VII and 3-chloroaniline. Flash chromatography eluent (DCM-EtOAc, 7:3). Yield: 74%; pale yellow solid; mp>260° C.; IR (KBr) νmax/cm−1 2849, 2226, 1643, 1611, 1577, 1461, 1377, 1354, 1306, 1218, 1161, 1128, 1070, 974, 875, 833; 1H NMR (300 MHz, DMSO-d6) δ 8.49 (d, 1H, J=9.0 Hz), 8.21 (s, 1H), 7.74 (d, 1H, J=9.0 Hz), 7.40-7.35 (m, 2H), 7.19-7.11 (m, 2H); HRMS calcd for C16H9N5SCl (M+H+): 338.0267, found 338.0259.