HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 21242492, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-(m-Trifluoromethylphenyl)-5-ethyl-1,3-oxazolidine | HCID 21242493 | — |
| Solvent | Isopropyl chloroformate | HCID 7917 | — |
| Product | HCID 21242492 | HCID 21242492 | — |
Reaction Steps
Four and four-tenths grams of 2-(m-trifluoromethylphenyl)-5-ethyl-1,3-oxazolidine was combined with 1.5 g of pyridine in 25 ml of methylene chloride and 2.1 ml of isopropyl chloroformate in 10 ml of methylene chloride was added with stirring. The mixture was left to stir overnight. It was worked up with 50 ml of 5% NaOH and 200 ml of water, dried with anhydrous MgSO4 and stripped under vacuum on the rotary evaporator. The structure was confirmed by NMR and infrared spectroscopy.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04824468 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-2f58b58641424efb9583af84a5f48a9e |
| Source note | uspto-grants-1989_04 |