Isopropyl isocyanate → HCID 21242491, compound

HRID 621380Notes

Reaction equation

HRID 621380 reaction equation
[F:1][C:2]([F:18])([F:17])[C:3]1[CH:4]=[C:5]([CH:10]2[NH:14][CH2:13][CH:12]([CH2:15][CH3:16])[O:11]2)[CH:6]=[CH:7][C:8]=1[Cl:9].[CH:19]([N:22]=[C:23]=[O:24])([CH3:21])[CH3:20]>CC(C)=O>[F:18][C:2]([F:17])([F:1])[C:3]1[CH:4]=[C:5]([CH:10]2[N:14]([C:23](=[O:24])[NH:22][CH:19]([CH3:21])[CH3:20])[CH2:13][CH:12]([CH2:15][CH3:16])[O:11]2)[CH:6]=[CH:7][C:8]=1[Cl:9]

Participants

4

Reactant 2

HCID 61277Isopropyl isocyanateHCID 21242490HCID 21242490, compound

Product 1

HCID 21242491HCID 21242491, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Four and six-tenths grams of 2-(3-trifluoromethyl-4-chlorophenyl)-5-ethyl-1,3-oxazolidine was combined with 1.5 g of isopropyl isocyanate in 25 ml of anhydrous acetone and allowed to stand overnight protected form moisture. The mixture was stripped on the rotary evaporator giving a gum. The structure was confirmed by NMR and infrared spectroscopy.

Workup

  1. customThe mixture was stripped on the rotary evaporator
  2. customgiving a gum

Sources & evidence

ORD record
ord-4441233e88d7486f933e036d57ec4431
Source dataset
uspto-grants-1989_04
Patent number
US04824468

Reaction notes

Loading…