Hydrochloric Acid → HCID 178418664, compound

HRID 6214Notes

Reaction equation

HRID 6214 reaction equation
C(OC([NH:8][C:9]1[CH:10]=[N:11][CH:12]=[CH:13][C:14]=1[SH:15])=O)(C)(C)C.[ClH:16]>C(O)(=O)C>[ClH:16].[NH2:8][C:9]1[CH:10]=[N:11][CH:12]=[CH:13][C:14]=1[SH:15]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 178418597HCID 178418597, compound

Product 1

HCID 178418664HCID 178418664, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent2×

Procedure

A 13.78 g (0.06 mol) sample of 3-(t-butyloxycarbonyl)amino-4-mercapto pyridine was dissolved with acetic acid (250 mL) and added to an ice cold solution of ~3N HCl in acetic acid which had been made by bubbling HCl(g) through glacial acetic acid (100 mL). After about four hours the resulting solid was filtered, washed with diethylether and dried in vacuo to yield 10.4 g (~100%) of the title compound. m.p.: >200° C.

Workup

  1. customby bubbling HCl(g) through glacial acetic acid (100 mL)
  2. filtrationAfter about four hours the resulting solid was filtered
  3. washwashed with diethylether
  4. customdried in vacuo

Sources & evidence

ORD record
ord-cc2ccc9b22a849008c758e58842ddd19
Source dataset
uspto-grants-1993_09
Patent number
US05247073

Reaction notes

Loading…