Cyromazine → HCID 21243170, compound

HRID 621427Notes

Reaction equation

HRID 621427 reaction equation
[CH3:1][O:2][CH2:3][C:4](Cl)=[O:5].[NH2:7][C:8]1[N:13]=[C:12]([NH2:14])[N:11]=[C:10]([NH:15][CH:16]2[CH2:18][CH2:17]2)[N:9]=1>N1C=CC=CC=1>[CH3:1][O:2][CH2:3][C:4]([NH:14][C:12]1[N:13]=[C:8]([NH:7][C:4](=[O:5])[CH2:3][O:2][CH3:1])[N:9]=[C:10]([NH:15][CH:16]2[CH2:18][CH2:17]2)[N:11]=1)=[O:5]

Participants

4

Reactant 2

HCID 47866CyromazineHCID 96623Methoxyacetyl chloride

Product 1

HCID 21243170HCID 21243170, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Conditions

Temperature
55 °C

Procedure

7.2 g of methoxyacetyl chloride are slowly added dropwise to a suspension of 5.0 g of 2,4-diamino-6-cyclopropylamino-1,3,5-triazine in 50 ml of pyridine. The reaction mixture is subsequently stirred for 1 hour at 55° C. and then for 16 hours at room temperature. After filtration of the reaction mixture, washing of the filter residue with water and finally drying, the product is obtained as white crystalline powder having a melting point of 175°-180° C.

Workup

  1. waitfor 16 hours at room temperature
  2. filtrationAfter filtration of the reaction mixture
  3. washwashing of the filter residue with water
  4. customfinally drying
  5. customthe product is obtained as white crystalline powder

Sources & evidence

ORD record
ord-575bb544b3f7463cbafef8e1b91c713a
Source dataset
uspto-grants-1989_04
Patent number
US04824845

Reaction notes

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