Hydrogen Bromide → HCID 21242911, compound

HRID 621453Notes

Reaction equation

HRID 621453 reaction equation
COC1C=C(SC)C2CCN(C)CCC=2C=1.Cl.C[O:19][C:20]1[CH:21]=[C:22]([S:32]([CH3:35])(=[O:34])=[O:33])[C:23]2[CH2:29][CH2:28][N:27]([CH3:30])[CH2:26][CH2:25][C:24]=2[CH:31]=1.[BrH:36]>>[BrH:36].[OH:19][C:20]1[CH:21]=[C:22]([S:32]([CH3:35])(=[O:34])=[O:33])[C:23]2[CH2:29][CH2:28][N:27]([CH3:30])[CH2:26][CH2:25][C:24]=2[CH:31]=1

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 21242913HCID 21242913, compoundHCID 21242957HCID 21242957, compound

Product 1

HCID 21242911HCID 21242911, compound

Procedure

Following the procedure of Example 4, Method B, 8-methoxy-3-methyl-6-methylthio-2,3,4,5-tetrahydro-1H-3-benzazepine is converted to 8-methoxy-3-methyl-6-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride which is treated with hydrobromic acid to give 8-hydroxy-3-methyl-6-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide.

Sources & evidence

ORD record
ord-9ea14b0955be4868a7683c9806491772
Source dataset
uspto-grants-1989_04
Patent number
US04824839

Reaction notes

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