HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → SK&F 103829
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 8-hydroxy-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide | HCID 21242877 | — |
| Product | SK&F 103829 | HCID 130981 | — |
Reaction Steps
8-Hydroxy-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide was treated with ammonium hydroxide. The resulting mixture was filtered to give 8-hydroxy-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine, m.p. 241°-242°. This was treated with methanesulfonic acid to give the methanesulfonate, m.p. 267°-269°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04824839 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-e4234953389346b58c9e06c870aec087 |
| Source note | uspto-grants-1989_04 |