Hydrochloric Acid → HCID 178448666, compound

Participants

Reaction Steps

To a suspension of 5-butyl-3-methylamino-7-(4-nitrobenzyl)pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione (1 g, 2.6 mM) in concentrated hydrochloric acid (5 ml) and ethanol (2.5 ml) was added dropwise a solution of stannous chloride (3.75 g) in ethanol (5 ml) at room temperature with stirring. The mixture was stirred at room temperature for 24 hours and concentrated to dryness. The residue was crystallized from hot water to give yellow crystals (0.42 g, 46%), m.p. >310° C.

Provenance & Evidence