Water → HCID 178504595, compound

HRID 621655Notes

Reaction equation

HRID 621655 reaction equation
[OH:1][C:2]1[N:7]2[N:8]=[CH:9][C:10]([C:11]3[CH:16]=[CH:15][C:14]([S:17][CH3:18])=[CH:13][CH:12]=3)=[C:6]2[N:5]=[CH:4][N:3]=1.I([O-])(=O)(=O)=[O:20].[Na+].O>CO>[OH:1][C:2]1[N:7]2[N:8]=[CH:9][C:10]([C:11]3[CH:16]=[CH:15][C:14]([S:17]([CH3:18])=[O:20])=[CH:13][CH:12]=3)=[C:6]2[N:5]=[CH:4][N:3]=1

Participants

5

Reactant 3

HCID 962WaterHCID 23667635Sodium periodateHCID 178503117HCID 178503117, compound

Product 1

HCID 178504595HCID 178504595, compoundYield 65.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a suspension of 4-hydroxy-8-(4-methylthiophenyl)pyrazolo[1,5-a]-1,3,5-triazine (258 mg) and sodium metaperiodate (430 mg) in methanol (20 ml) is added water (0.5 ml), and the mixture is stirred at room temperature for 40 hours. The insoluble material is separated by filtration, washed with water and dried to give the title compound (180 mg).

Workup

  1. customThe insoluble material is separated by filtration
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-ccc1779556774c6a87a3a1c26e3219e5
Source dataset
uspto-grants-1989_04
Patent number
US04824834

Reaction notes

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