Ethanol → HCID 13770109, compound

HRID 622084Notes

Reaction equation

HRID 622084 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:25]=[CH:26][CH:27]=1)[CH:7]=[C:8]([C:17](=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:9](=[O:16])CC(OCC)=O)([O-:3])=[O:2].[O:28]1[CH2:33][CH2:32][N:31]([CH:34]2[CH2:39][CH2:38][CH2:37][CH2:36][CH2:35]2)[CH2:30][CH2:29]1.[CH2:40]([OH:42])[CH3:41]>>[O:28]1[CH2:33][CH2:32][N:31]([C:34]23[O:24][C:17]([C:18]4[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=4)=[C:8]([C:9]([O:42][CH2:40][CH3:41])=[O:16])[CH:7]([C:6]4[CH:25]=[CH:26][CH:27]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=4)[CH:39]2[CH2:38][CH2:37][CH2:36][CH2:35]3)[CH2:30][CH2:29]1

Participants

4

Reactant 3

HCID 702EthanolHCID 229384-CyclohexylmorpholineHCID 70416511HCID 70416511, compound

Product 1

HCID 13770109HCID 13770109, compound

Procedure

A solution of 10.9 g (0.033 mole) of ethyl 3-nitrobenzylidenebenzoylacetoacetate and 5.6 g (0.033 mole) of morpholinocyclohexane in 80 ml of ethanol is boiled under reflux for 4 hours. The solution is concentrated and the residue is triturated with ether, filtered off with suction and recrystallized from ethanol.

Workup

  1. temperatureunder reflux for 4 hours
  2. concentrationThe solution is concentrated
  3. customthe residue is triturated with ether
  4. filtrationfiltered off with suction
  5. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-322e4f1e9fcb482d876007b595fc1c6a
Source dataset
uspto-grants-1988_09
Patent number
US04769375

Reaction notes

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