Hydrochloric Acid → HCID 16752261, compound

HRID 622094Notes

Reaction equation

HRID 622094 reaction equation
Cl.[C:2]([C:10]1[CH:11]=[C:12]([C:18]#[N:19])[C:13](=[O:17])[NH:14][C:15]=1[CH3:16])(=[O:9])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[OH2:20]>>[C:2]([C:10]1[CH:11]=[C:12]([C:18]([NH2:19])=[O:20])[C:13](=[O:17])[NH:14][C:15]=1[CH3:16])(=[O:9])[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 13565732HCID 13565732, compound

Product 1

HCID 16752261HCID 16752261, compound

Procedure

Admix 80 ml 35% hydrochloric acid and 20 g (0.078 mole) of 5-benzoyl-1,2-dihydro-6-methyl-2-oxo-3-pyridine carbonitrile, stir the mixture at 40° C. for 5 hours, cool, and dilute the resulting mixture with 80 ml water. Collect the title compound as a precipitate.

Workup

  1. temperaturecool
  2. customCollect the title compound as a precipitate

Sources & evidence

ORD record
ord-96ecb8872f0d4248bc4769b330815364
Source dataset
uspto-grants-1988_09
Patent number
US04769380

Reaction notes

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