HCID 13813644, compound → HCID 14257077, compound

HRID 622097Notes

Reaction equation

HRID 622097 reaction equation
[C:1]1([C:7]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)([C:9]2[CH:10]=[N:11][CH:12]=[N:13][CH:14]=2)O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>S(=O)(=O)(O)O>[C:1]1([CH:7]2[C:9]3[CH:10]=[N:11][CH:12]=[N:13][C:14]=3[C:20]3[C:15]2=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 1

HCID 13813644HCID 13813644, compound

Product 1

HCID 14257077HCID 14257077, compoundYield 118.1%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

Ten grams of α, α-diphenyl-5-pyrimidinemethanol were stirred in 50 ml of sulfuric acid for approximately 18 hours. The solution was poured onto ice and the resulting solids were recovered by filtration providing 11 g of the desired title product. Recrystallization from diethyl ether provided material with a melting point of 148°-150° C.

Workup

  1. additionThe solution was poured onto ice
  2. filtrationthe resulting solids were recovered by filtration

Sources & evidence

ORD record
ord-dd7a51888b1e439690b50f286d6650ef
Source dataset
uspto-grants-1988_09
Patent number
US04769378

Reaction notes

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