反应详情

5-Bromo-3-hydroxyphthalide (49 gm) was slurred in 200 ml isopropanol. Hydrazine (20 ml) was added and the mixture refluxed for 2 hours. The reaction mixture was allowed to cool and the product filtered off, washed with isopropanol and dried. The product weighed 46.8 gm and melted at 280°-283° C.

1. temperaturethe mixture refluxed for 2 hours
2. temperatureto cool
3. filtrationthe product filtered off
4. washwashed with isopropanol
5. customdried