3,4,5,6-Tetrafluorophthalic acid → 2,3,4,5-Tetrafluorobenzoic acid

HRID 622254Notes

Reaction equation

HRID 622254 reaction equation
[F:1][C:2]1[C:10]([F:11])=[C:9]([F:12])[C:8]([F:13])=[C:4](C(O)=O)[C:3]=1[C:14]([OH:16])=[O:15]>O>[F:1][C:2]1[C:10]([F:11])=[C:9]([F:12])[C:8]([F:13])=[CH:4][C:3]=1[C:14]([OH:16])=[O:15]

Participants

3

Reactant 1

HCID 695443,4,5,6-Tetrafluorophthalic acid2×

Product 1

HCID 2975492,3,4,5-Tetrafluorobenzoic acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Decarboxylation of 3,4,5,6-tetrafluorophthalic acid was carried out by following the procedure of Example 1, except that 238 g of 3,4,5,6-tetrafluorophthalic acid and 480 g of water were used. The reaction product was separated by following the procedure of Example 1 [pH 1.33 at 30° C. at the time of charging]. This example was found to have produced 2,3,4,5-tetrafluorobenzoic acid in a yield of 87.5 mole %.

Workup

  1. customThe reaction product was separated
  2. customat 30° C.

Sources & evidence

ORD record
ord-d00bc4ae4f32468f97ebf1c81415619d
Source dataset
uspto-grants-1988_09
Patent number
US04769492

Reaction notes

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