3,4,5,6-Tetrafluorophthalic acid → 2,3,4,5-Tetrafluorobenzoic acid

Participants

Reaction Steps

Decarboxylation of 3,4,5,6-tetrafluorophthalic acid was carried out by following the procedure of Example 1, except that 238 g of 3,4,5,6-tetrafluorophthalic acid and 480 g of water were used. The reaction product was separated by following the procedure of Example 1 [pH 1.33 at 30° C. at the time of charging]. This example was found to have produced 2,3,4,5-tetrafluorobenzoic acid in a yield of 87.5 mole %.

Provenance & Evidence