1-[1-(2-Chlorophenyl)butyl]-1H-imidazole-5-carboxylic acid → HCID 23707461, compound

Participants

Reaction Steps

A mixture of 1 part of 1-[1-(2-chlorophenyl)butyl]-1H-imidazole-5-carboxylic acid, 80 parts of methanol and 35.9 parts of a potassium methoxide solution 0.1N was stirred for 1 hour at reflux temperature. The reaction mixture was evaporated and the residue was dried in a dry pistol at 70° C., yielding 0.34 parts (26.7%) of potassium 1-[1-(2-chlorophenyl)butyl]-1H-imidazole-5 -carboxylate dihydrate; mp. 70.7° C. (compound 2.14).

Provenance & Evidence