Thionyl Chloride → HCID 14273862, compound

HRID 622334Notes

Reaction equation

HRID 622334 reaction equation
[C:1]([C:6]1[CH:22]=[CH:21][C:9]([O:10][CH:11]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[C:12](O)=[O:13])=[C:8]([Cl:23])[CH:7]=1)([CH2:4][CH3:5])([CH3:3])[CH3:2].S(Cl)([Cl:26])=O>C1(C)C=CC=CC=1>[C:1]([C:6]1[CH:22]=[CH:21][C:9]([O:10][CH:11]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[C:12]([Cl:26])=[O:13])=[C:8]([Cl:23])[CH:7]=1)([CH2:4][CH3:5])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 14273861HCID 14273861, compound

Product 1

HCID 14273862HCID 14273862, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
60 °C

Procedure

A mixture of 46 g of 2-(4-t-amyl-2-chlorophenoxy)octanoic acid and 46 ml of toluene was heated to 60° C., and 20.3 ml of thionyl chloride was slowly added thereto dropwise while stirring. After allowing the mixture to react at that temperature for 2 hours, the excess thionyl chloride and toluene were removed by distillation under reduced pressure to obtain 48 g of 2-(4-t-amyl-2-chlorophenoxy)octanoic acid chloride.

Workup

  1. customto react at that temperature for 2 hours
  2. customthe excess thionyl chloride and toluene were removed by distillation under reduced pressure

Sources & evidence

ORD record
ord-bad5b7883c8643c08f6d7bd202f0a747
Source dataset
uspto-grants-1988_09
Patent number
US04770988

Reaction notes

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