Thionyl Chloride → HCID 14273862, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 46 g of 2-(4-t-amyl-2-chlorophenoxy)octanoic acid and 46 ml of toluene was heated to 60° C., and 20.3 ml of thionyl chloride was slowly added thereto dropwise while stirring. After allowing the mixture to react at that temperature for 2 hours, the excess thionyl chloride and toluene were removed by distillation under reduced pressure to obtain 48 g of 2-(4-t-amyl-2-chlorophenoxy)octanoic acid chloride.

Provenance & Evidence