Methyl 2-chloroethanimidate--hydrogen chloride (1/1) → 2-(4-Methoxyiminopiperidin-1-yl)-2-iminoethylchloride hydrochloride

Participants

Reaction Steps

2 ml of a methanolic solution containing 1.064 g of 4-methoxyiminopiperidine was added to a solution of 1.195 g of methyl 2-chloroacetimidate hydrochloride in 4 ml of absolute methanol, and the mixture was stirred at room temperature for 2 hours. After completion of the reaction, the solvent was distilled off and the concentrate was mixed with anhydrous ether. The crystals which separated out were collected by filtration and washed with ether, giving 1.5 g of 2-(4-methoxyiminopiperidin-1-yl)-2-iminoethylchloride hydrochloride.

Provenance & Evidence