Echinopsine → HCID 21291473, compound

Participants

Reaction Steps

1-Methyl-4-quinolone (2 g) was heated with chlorosulphonic acid (5 ml) at 125° for 2.5 hours. The reaction mixture was cooled to room temperature and then carefully poured onto crushed ice (300 ml). The precipitated solid was collected by filtration and then dried to give the novel compound 1-methyl-4-oxo-1,4-dihydroquinoline-3-sulphonyl chloride, m.p. 313°-315°.

Provenance & Evidence