Methylamine → HCID 11779977, compound

HRID 622684Notes

Reaction equation

HRID 622684 reaction equation
[CH3:1][N:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5](=[O:12])[C:4]([S:13](Cl)(=[O:15])=[O:14])=[CH:3]1.[CH3:17][NH2:18]>>[CH3:1][N:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5](=[O:12])[C:4]([S:13]([NH:18][CH3:17])(=[O:15])=[O:14])=[CH:3]1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 21291473HCID 21291473, compound

Product 1

HCID 11779977HCID 11779977, compound

Procedure

A mixture of 1-methyl-4-oxo-1,4-dihydroquinoline-3-sulphonyl chloride (3.56 g) and aqueous methylamine (30% w/v; 100 ml) was stirred at room temperature for 1 hour. The precipitated solid was filtered off, washed with water and crystallised from aqueous acetic acid to give the compound 1,N-dimethyl-4-oxo-1,4-dihydroquinoline-3-sulphonamide, m.p. 248°-250°.

Workup

  1. filtrationThe precipitated solid was filtered off
  2. washwashed with water
  3. customcrystallised from aqueous acetic acid

Sources & evidence

ORD record
ord-b22046b16f2b4eb3acd6435e5f9f36fd
Source dataset
uspto-grants-1988_09
Patent number
US04772614

Reaction notes

Loading…