Dimethylamine → HCID 21291465, compound

Participants

Reaction Steps

1-Methyl-4-oxo-7-trifluoromethyl-1,4-dihydroquinoline-3-sulphonyl chloride (12.4 g) was added to a stirred solution of dimethylamine in industrial methylated spirit (33% w/w; 230 ml) and the mixture was kept at ambient temperature for 27 hours. The mixture was evaporated to dryness and the residue was recrystallised from industrial methylated spirit using charcoal to give the novel compound 1,N,N-trimethyl-4-oxo-7-trifluoromethyl-1,4-dihydroquinoline-3-sulphonamide, m.p. 221°-223°.

Provenance & Evidence