HCID 70358781, compound → HCID 178484878, compound

Participants

Reaction Steps

3.37 g (10 mmol) of (+)-(7S)-5,6,7,8-tetra-hydro-7-(methoxycarbonyl)-2-methyl-5-oxoimidazo[1,5-c]pyrimidine hydroiodide is heated under reflux in 40 ml of 6N HCl until no starting compound can be detected any longer by thin-layer chromatography (6-8 hours). Then, the hydrochloric acid is withdrawn under vacuum, the oily residue is taken up in ethanol and crystallized by addition of ether.

Provenance & Evidence