反应详情

50 mg of sodium was dissolved in 25 ml of dry ethanol containing 3 g of molecular sieves (4 Å) and 0.5 g of cyclopropylcarboxamide oxime was added to this mixture and thereupon 0.6 g of ethyl 4,5-dihydro-5-methyl-4-oxo-imidazo(1,5-a)quinoxaline-3-carboxylate. The resulting mixture was refluxed for 2 hours, whereafter the molecular sieves were filtered off. The title compound was isolated after evaporation of the solvent in vacuo, followed by addition of icewater and filtration. Yield 0.4 g of title compound. M.p. 224.7-225.6° C.

1. additionwas added to this mixture
2. temperatureThe resulting mixture was refluxed for 2 hours, whereafter the molecular sieves
3. filtrationwere filtered off