1-Bromohexane → HCID 10704646, compound

HRID 623229Notes

Reaction equation

HRID 623229 reaction equation
[C:1]1([C:7]2[NH:11][N:10]=[N:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C[O-].[Na+].Br[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]>C(O)C>[CH2:16]([N:8]1[C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[N:11][N:10]=[N:9]1)[CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]

Participants

5

Reactant 3

HCID 81011-BromohexaneHCID 10942334Sodium MethoxideHCID 178418369HCID 178418369, compound

Product 1

HCID 10704646HCID 10704646, compoundYield 46%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

5-Phenyltetrazole (29.2 g, 0.2 mole) was placed in 300 ml of ethanol and sodium methylate (11 g, 0.2 mole) added. On the addition of bromohexane (33 g, 0.2 mole), the solution cleared immediately. The mixture slowly became cloudy on four hours refluxing. Filtering followed by stripping gave 21.2 g of a yellow liquid.

Workup

  1. temperaturerefluxing
  2. filtrationFiltering

Sources & evidence

ORD record
ord-b55f7d7bddff4c8f874a2e7ed00c0aaa
Source dataset
uspto-grants-1988_09
Patent number
US04774266

Reaction notes

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