Benzene → HCID 14049266, compound

HRID 623236Notes

Reaction equation

HRID 623236 reaction equation
[CH2:1]([Sn:11](Cl)([CH2:19][C:20]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)([CH3:22])[CH3:21])[C:12]1[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=1)[C:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)([CH3:4])[CH3:3].[F-:30].[K+].C1C=CC=CC=1>O>[CH2:1]([Sn:11]([F:30])([CH2:19][C:20]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)([CH3:22])[CH3:21])[C:12]1[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=1)[C:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)([CH3:4])[CH3:3]

Participants

5

Reactant 3

HCID 241BenzeneHCID 522689Potassium FluorideHCID 14049251HCID 14049251, compound

Product 1

HCID 14049266HCID 14049266, compoundYield 79.5%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture consisting of the crude dineophyl-parafluorophenyltin chloride (50 g) and potassium fluoride (5.8 g, 0.1 mol) was heated for 2 hours in the presence of benzene (120 g) and water (23 g). The aqueous layer of the reaction mixture was removed, and the organic layer was washed with water, filtered and concentrated under reduced pressure. The residue thus obtained was crystallized from petroleum ether to give 38.5 g of dineophyl-parafluorophenyltin fluoride as a white solid.

Workup

  1. customThe aqueous layer of the reaction mixture was removed
  2. washthe organic layer was washed with water
  3. filtrationfiltered
  4. concentrationconcentrated under reduced pressure
  5. customThe residue thus obtained
  6. customwas crystallized from petroleum ether

Sources & evidence

ORD record
ord-97e060de34494022988ca3ce0974043b
Source dataset
uspto-grants-1988_09
Patent number
US04774235

Reaction notes

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