関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Tert-Butylamine | HCID 6385 | — |
| 反応物 | Methyl 2-amino-3,5-dichlorobenzoate | HCID 613050 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | N-tert-butyl-2-amino-3,5-dichlorobenzamide | HCID 118496623 | 90.4% |
反応手順
To a 100 mL round-bottom flask, 0.1 mol of 2-amino-3,5-dichlorobenzoic acid methyl ester having a structure as shown in VIII-1, 100 mL of methanol, and 0.4 mol of tert-butylamine were added, heated to 64° C. and reacted for 5 hours, after treatment 23.5 grams of N-tert-butyl-2-amino-3,5-dichlorobenzamide having a structural formula of III-1 was obtained, and the yield was 90.4%;
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09301529B2 |
|---|
| 出典データセット | uspto-grants-2016_04 |
|---|
| ORD ID | ord-d84848f7159b4522a4d7d69ea5449e08 |
|---|
| 出典メモ | uspto-grants-2016_04 |
|---|
