Dodecylamine → HCID 67510084, compound

HRID 623470Notes

Reaction equation

HRID 623470 reaction equation
Cl[C:2]1[N:10]=[C:9]([O:11][CH2:12][C:13]([F:16])([F:15])[F:14])[C:8]([F:17])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].CCCCCCCCCCCCN>>[F:17][C:8]1[C:9]([O:11][CH2:12][C:13]([F:15])([F:16])[F:14])=[N:10][CH:2]=[C:3]([CH:7]=1)[C:4]([OH:6])=[O:5]

Participants

3

Reactant 2

HCID 13583DodecylamineHCID 87426433HCID 87426433, compound

Product 1

HCID 67510084HCID 67510084, compoundYield 75%

Procedure

The title compound is prepared in 75% yield (21.0 g, a white solid) from 2-chloro-5-fluoro-6-(2,2,2-trifluoroethoxy)nicotinic acid (32.2 g, 118 mmol, Step-1 of Amine-12) by the similar manner in Step-4 of Amine-12.

Sources & evidence

ORD record
ord-d1df65349233427992331bb73acfe417
Source dataset
uspto-grants-2016_04
Patent number
US09302991B2

Reaction notes

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