HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2,2,2-Trifluoroethoxy)ethan-1-ol → HCID 67509694, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2,2,2-Trifluoroethoxy)ethan-1-ol | HCID 255854 | — |
| Reactant | 1-(6-Chloropyridin-3-yl)ethan-1-one | HCID 2779698 | — |
| Product | HCID 67509694 | HCID 67509694 | 50% |
Reaction Steps
The title compound is prepared in 50% yield (1.67 g, colorless oil) from 1-(6-chloropyridin-3-yl)ethanone (2.0 g, 12.9 mmol) and 2-(2,2,2-trifluoroethoxy)ethanol instead of 2,2,2-trifluoroethanol by the similar manner in Step-1 of Amine-2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-b7fd9e79329f4591a1c0d0fc34e96ed3 |
| Source note | uspto-grants-2016_04 |