HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Difluoroethan-1-ol → HCID 82006899, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Difluoroethan-1-ol | HCID 136187 | — |
| Reactant | 1-(6-Chloropyridin-3-yl)ethan-1-one | HCID 2779698 | — |
| Product | HCID 82006899 | HCID 82006899 | 71% |
Reaction Steps
The title compound is prepared in 71% yield (1.34 g, a white solid) from 1-(6-chloropyridin-3-yl)ethanone (1.5 g, 9.64 mmol) and 2,2-difluoroethanol instead of 2,2,2-trifluoroethanol by the similar manner in Step-1 of Amine-2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-8c97458e02e24a0ea9fecbc932835807 |
| Source note | uspto-grants-2016_04 |