HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → HCID 87426340, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | HCID 87426801 | HCID 87426801 | — |
| Product | HCID 87426340 | HCID 87426340 | 99% |
Reaction Steps
The title compound is prepared in >99% yield (0.71 g, yellow oil) from 2,2,2-trifluoroethyl 2-chloro-6-(2,2,2-trifluoroethoxy)nicotinate (0.75 g, 2.04 mmol, Step-1 of Amine-37) and 1-methylpiperazine instead of morpholine by the similar manner in Step-2 of Amine-37.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-17018e544472435c8a73bbed138b5db3 |
| Source note | uspto-grants-2016_04 |