HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 87426398, compound → HCID 87426381, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 87426398 | HCID 87426398 | — |
| Reactant | HCID 178418750 | HCID 178418750 | — |
| Product | HCID 87426381 | HCID 87426381 | 88% |
Reaction Steps
The title compound is prepared in 88% yield (660 mg, clear colorless oil) from methyl 5-bromo-6-(2,2-difluoroethoxy)nicotinate (900 mg, 3.0 mmol, Step-2) and diethylzinc instead of dimethylzinc by the similar manner in Step-3 of Amine-27.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-918cbf8d03b34840a6fc01a0ec899fd1 |
| Source note | uspto-grants-2016_04 |