Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 623529Generated: October 31, 2026

1-[2-Fluoro-3-(trifluoromethyl)phenyl]ethan-1-one → HCID 67510352, compound

https://huagongshe.com/reaction/623529

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[2-Fluoro-3-(trifluoromethyl)phenyl]ethan-1-oneHCID 2737529—
Reactanttert-Butylsulfinamide, (R)-(+)-HCID 10964479—
ProductHCID 67510352HCID 6751035256%

Reaction Steps

The title compound is prepared in 56% yield (511 mg, a white solid) from 1-(2-fluoro-3-(trifluoromethyl)phenyl)ethanone (600 mg, 2.91 mmol, Step-2) and (R)-2-methylpropane-2-sulfinamide (529 mg, 4.37 mmol) by the similar manner in Step-4 of Amine-1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09302991B2
Source datasetuspto-grants-2016_04
ORD IDord-61e41916fe824be4a39133526deef34f
Source noteuspto-grants-2016_04