HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Difluoroethan-1-ol → HCID 87426976, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Difluoroethan-1-ol | HCID 136187 | — |
| Reactant | HCID 87426205 | HCID 87426205 | — |
| Product | HCID 87426976 | HCID 87426976 | 72% |
Reaction Steps
The title compound is prepared in 72% yield (0.94 g, a white solid) from 1-(6-chloro-5-methoxypyridin-3-yl)ethanone (1.04 g, 5.60 mmol, Step-2 of Amine-22) and 2,2-difluoroethanol instead of 2,2,2-trifluoroethanol by the similar manner in Step-1 of Amine-2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-191931730e69467ebe55dd029b4245aa |
| Source note | uspto-grants-2016_04 |