HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutyryl chloride → 4-Pyridinecarboxylic acid, 2-[(2-methyl-1-oxopropyl)amino]-, methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutyryl chloride | HCID 62325 | — |
| Reactant | methyl 2-aminoisonicotinate hydrochloride（WS204501） | HCID 67509862 | — |
| Product | 4-Pyridinecarboxylic acid, 2-[(2-methyl-1-oxopropyl)amino]-, methyl ester | HCID 67509177 | 93% |
Reaction Steps
The title compound is prepared in 93% yield (2.20 g, a yellow solid) from methyl 2-aminoisonicotinate hydrochloride (2.00 g, 10.6 mmol) and isobutyryl chloride by the similar manner in Step-1 of Carboxylic acid-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-00e82cd9e687489cb5475f1a037c5a2a |
| Source note | uspto-grants-2016_04 |