Butyryl chloride → HCID 67509689, compound

HRID 623559Notes

Reaction equation

HRID 623559 reaction equation
Cl.[NH2:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][N:12]=1)[C:6]([O:8][CH3:9])=[O:7].[C:13](Cl)(=[O:17])[CH2:14][CH2:15][CH3:16]>>[C:13]([NH:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][N:12]=1)[C:6]([O:8][CH3:9])=[O:7])(=[O:17])[CH2:14][CH2:15][CH3:16]

Participants

3

Reactant 2

HCID 8855Butyryl chlorideHCID 67509862methyl 2-aminoisonicotinate hydrochloride（WS204501）

Product 1

HCID 67509689HCID 67509689, compoundYield 82%

Procedure

The title compound is prepared in 82% yield (1.94 g, a white solid) from methyl 2-aminoisonicotinate hydrochloride (2.00 g, 10.6 mmol) and butyryl chloride by the similar manner in Step-1 of Carboxylic acid-1.

Sources & evidence

ORD record
ord-a0be20038da74f918955558978707c20
Source dataset
uspto-grants-2016_04
Patent number
US09302991B2

Reaction notes

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