HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pivaloyl chloride → Methyl 2-(2,2-dimethylpropanamido)pyridine-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pivaloyl chloride | HCID 62493 | — |
| Reactant | methyl 2-aminoisonicotinate hydrochloride（WS204501） | HCID 67509862 | — |
| Product | Methyl 2-(2,2-dimethylpropanamido)pyridine-4-carboxylate | HCID 17750159 | — |
Reaction Steps
The title compound is prepared in quantitative yield (1.25 g, colorless syrup) from methyl 2-aminoisonicotinate hydrochloride (1.00 g, 5.30 mmol) and pivaloyl chloride by the similar manner in Step-1 of Carboxylic acid-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-5f758960652640a5ae7f03a2bb1e955b |
| Source note | uspto-grants-2016_04 |