HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-Chloro-6-methylisonicotinate → Methyl 2-(2-acetoxy-2-methylpropanamido)-6-methylisonicotinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-Chloro-6-methylisonicotinate | HCID 2759833 | — |
| Reactant | 1-Amino-2-methyl-1-oxopropan-2-yl acetate | HCID 12435542 | — |
| Product | Methyl 2-(2-acetoxy-2-methylpropanamido)-6-methylisonicotinate | HCID 67510446 | 80% |
Reaction Steps
The title compound is prepared in 80% yield (0.89 g, a yellow solid) from methyl 2-chloro-6-methylisonicotinate (0.70 g, 3.8 mmol) and 1-amino-2-methyl-1-oxopropan-2-yl acetate by the similar manner in Step-1 of Carboxylic acid-4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-c2262ef6324c4efca35108b0b21ad87f |
| Source note | uspto-grants-2016_04 |