HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminopyrimidine-4-carboxylic acid → HCID 67509939, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminopyrimidine-4-carboxylic acid | HCID 247194 | — |
| Reactant | 1-(6-(3,3,3-Trifluoropropoxy)pyridin-3-yl)ethanamine hydrochloride | HCID 67509338 | — |
| Product | HCID 67509939 | HCID 67509939 | 64% |
Reaction Steps
The title compound is prepared in 64% yield (100 mg, a white solid) from 1-(6-(3,3,3-trifluoropropoxy)pyridin-3-yl)ethanamine hydrochloride (120 mg, 0.4 mmol, Amine-21, single enantiomer) and 2-aminopyrimidine-4-carboxylic acid (62 mg, 0.4 mmol) by the similar manner in Step-1 of Example 8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-b09dd97d460e49308f6181d1e750d774 |
| Source note | uspto-grants-2016_04 |