HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-(2,2,2-Trifluoroethoxy)pyridin-3-yl)methanamine hydrochloride → 2-methyl-6-pivalamido-N-((6-(2,2,2-trifluoroethoxy)pyridin-3-yl)methyl)isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-(2,2,2-Trifluoroethoxy)pyridin-3-yl)methanamine hydrochloride | HCID 67508831 | — |
| Reactant | 2-Methyl-6-pivalamidoisonicotinic acid | HCID 67510013 | — |
| Product | 2-methyl-6-pivalamido-N-((6-(2,2,2-trifluoroethoxy)pyridin-3-yl)methyl)isonicotinamide | HCID 67508399 | — |
Reaction Steps
The title compound is prepared from 2-methyl-6-pivalamidoisonicotinic acid (30 mg, 0.06 mmol, Step-1) and (6-(2,2,2-trifluoroethoxy)pyridin-3-yl)methanamine hydrochloride (15 mg, 0.06 mmol) by the similar manner in Example 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-2873837edb2443cdb00710a80433b37b |
| Source note | uspto-grants-2016_04 |