HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Methoxycarbonyl)-6-methylisonicotinic acid → Methyl 4-(((2-methoxy-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)methyl)carbamoyl)-6-methylpicolinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Methoxycarbonyl)-6-methylisonicotinic acid | HCID 59570879 | — |
| Reactant | (2-Methoxy-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)methanamine hydrochloride | HCID 67510493 | — |
| Product | Methyl 4-(((2-methoxy-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)methyl)carbamoyl)-6-methylpicolinate | HCID 67510315 | — |
Reaction Steps
The title compound is prepared from (2-methoxy-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)methanamine hydrochloride (Amine-24) and 2-(methoxycarbonyl)-6-methylisonicotinic acid by the similar manner in Step-1 of Example 8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-cfbd5c1806754b428cc8a764411c7cb1 |
| Source note | uspto-grants-2016_04 |